Wet-spinning of sodium alginate fibers: Establishing reproducible structure–process–property relationships for potential biomedical textile applications
Khmais Zdiri, Annaëlle Erard, Aurélie Cayla, Fabien Salaun
Vol. 20., No.10., Pages 1072-1088, 2026
DOI: 10.3144/expresspolymlett.2026.78
DOI: 10.3144/expresspolymlett.2026.78
GRAPHICAL ABSTRACT

ABSTRACT
Alginate fibers are attractive for biomedical applications because of their biocompatibility and mild ionic crosslinking. This study investigated the effects of alginate concentration, calcium chloride (CaCl2) concentration, and coagulation time on fiber morphology and mechanical properties. Alginate solutions (6–10 wt%) were wet-spun through a 0.58 mm spinneret into CaCl2 baths (0.5–3 wt%). Rheological analysis showed dominant viscous behavior (G″ > G′), ensuring stable extrusion without premature gelation. Fiber morphology was examined by optical microscopy and scanning electron microscopy, while mechanical properties were evaluated by tensile testing. Among the conditions investigated, 8 wt% alginate, 1 wt% CaCl2, and 5 min coagulation provided smooth and homogeneous fibers with favorable mechanical performance. Higher CaCl2 concentrations or longer coagulation times were associated with more heterogeneous fibrillar structures and, under some conditions, reduced mechanical performance. These results provide insights into process–structure–property relationships in wet-spun alginate fibers and identify favorable processing conditions among those investigated for producing flexible filaments with characteristics of interest for biomedical textile materials, including knitted wound dressings. Biomedical performance and biocompatibility were not evaluated in the present study.
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